VCP Antikörper (AA 10-512)

Produktnummer ABIN7826030

Dieser Anti-VCP Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von VCP in WB und IHC. Geeignet für Zebrafisch (Danio rerio).

Kurzübersicht für VCP Antikörper (AA 10-512) (ABIN7826030)

Target: VCP (Valosin Containing Protein (VCP))

Reaktivität: Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VCP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-VCP Antikörper

Bindungsspezifität: AA 10-512

Verwendungszweck: Anti-Zebrafish VCP Antibody

Produktmerkmale: Anti-Zebrafish VCP Antibody catalog # AZQ7ZU99. Tested in WB, IHC applications. This antibody reacts with Zebrafish. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived zebrafish VCP recombinant protein (Position: D10-K512).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Zebrafish
Immunohistochemistry, 2-5 μg/mL, Zebrafish

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu VCP

Target: VCP (Valosin Containing Protein (VCP))

Andere Bezeichnung: VCP

Hintergrund: Predicted to enable ATP hydrolysis activity and polyubiquitin modification-dependent protein binding activity. Acts upstream of or within several processes, including heart contraction, regulation of catabolic process, and striated muscle cell development. Predicted to be located in cytoplasm and site of double-strand break. Predicted to be part of VCP-NPL4-UFD1 AAA ATPase complex. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including brain, digestive system, eye, fin bud, and trunk musculature. Human ortholog(s) of this gene implicated in several diseases, including Charcot-Marie-Tooth disease type 2Y, Paget's disease of bone, frontotemporal dementia and/or amyotrophic lateral sclerosis 6, inclusion body myopathy with early-onset Paget disease of bone with or without frontotemporal dementia 1, and inclusion body myositis. Orthologous to human VCP (valosin containing protein).

Molekulargewicht: 97 kDa

Pathways: ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Ubiquitin Proteasome Pathway