PARL Antikörper (Middle Region)
Kurzübersicht für PARL Antikörper (Middle Region) (ABIN7825716)
Target
Alle PARL Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Verwendungszweck
- Anti-PARL Antibody
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Kreuzreaktivität (Details)
- No cross-reactivity with other proteins
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Produktmerkmale
- Anti-PARL Antibody catalog # A08686-1. Tested in WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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Aufreinigung
- Immunogen affinity purified.
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Immunogen
- A synthetic peptide corresponding to a sequence in the middle region of human PARL. Human PARL shares 98.8% amino acid (aa) sequence identity with both mouse and rat PARL.
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Isotyp
- IgG
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Applikationshinweise
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Konzentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- PARL (Presenilin Associated, Rhomboid-Like (PARL))
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Andere Bezeichnung
- PARL
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Hintergrund
- This gene encodes a member of the rhomboid family of intramembrane serine proteases that is localized to the inner mitochondrial membrane. The encoded protein regulates mitochondrial remodeling and apoptosis through regulated substrate proteolysis. Proteolytic processing of the encoded protein results in the release of a small peptide, P-beta, which may transit to the nucleus. Mutations in this gene may be associated with Parkinson's disease.
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Molekulargewicht
- 40 kDa
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Gen-ID
- 55486
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UniProt
- Q9H300
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Pathways
- Autophagie
Target
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