PIK3C2A Antikörper (AA 22-1523)

Produktnummer ABIN7825686

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PIK3C2A in WB, ELISA, ICC und IF. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für PIK3C2A Antikörper (AA 22-1523) (ABIN7825686)

Target: PIK3C2A (Phosphoinositide-3-Kinase, Class 2, alpha Polypeptide (PIK3C2A))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PIK3C2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Produktdetails anti-PIK3C2A Antikörper

Bindungsspezifität: AA 22-1523

Verwendungszweck: Anti-PIK3C2A Antibody

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human PIK3C2A shares 89.7% amino acid (aa) sequence identity with mouse PIK3C2A.

Produktmerkmale: Anti-PIK3C2A Antibody. Tested in WB, ICC/IF, ELISA applications. This antibody reacts with Human, Mouse.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human PIK3C2A recombinant protein (Position: R22-E1523). Human PIK3C2A shares 89.7% amino acid (aa) sequence identity with mouse PIK3C2A.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Mouse Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human ELISA, 0.1-0.5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu PIK3C2A

Target: PIK3C2A (Phosphoinositide-3-Kinase, Class 2, alpha Polypeptide (PIK3C2A))

Andere Bezeichnung: PIK3C2A

Hintergrund:

Background: The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling.

Gene Full Name: phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha

Molekulargewicht: 191 kDa

Gen-ID: 5286

UniProt: O00443

Pathways: EGFR Signaling Pathway, Inositol Metabolic Process, Platelet-derived growth Factor Receptor Signaling