Anti-PIK3C2A Antibody catalog # A03530-2. Tested in WB, ICC/IF, ELISA applications. This antibody reacts with Human, Mouse. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
Aufreinigung
Immunogen affinity purified.
Immunogen
E.coli-derived human PIK3C2A recombinant protein (Position: R22-E1523). Human PIK3C2A shares 89.7% amino acid (aa) sequence identity with mouse PIK3C2A.
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
Target
PIK3C2A
(Phosphoinositide-3-Kinase, Class 2, alpha Polypeptide (PIK3C2A))
Andere Bezeichnung
PIK3C2A
Hintergrund
The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling.