PAK4 Antikörper (C-Term)
Kurzübersicht für PAK4 Antikörper (C-Term) (ABIN7825651)
Target
Alle PAK4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Verwendungszweck
- Anti-PAK4 Antibody
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Kreuzreaktivität (Details)
- No cross-reactivity with other proteins
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Produktmerkmale
- Anti-PAK4 Antibody catalog # A01723-3. Tested in WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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Aufreinigung
- Immunogen affinity purified.
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Immunogen
- A synthetic peptide corresponding to a sequence at the C-terminus of human PAK4.
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Isotyp
- IgG
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Applikationshinweise
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Western blot, 0.25-0.5 μg/mL, Human
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Konzentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- PAK4 (P21-Activated Kinase 4 (PAK4))
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Andere Bezeichnung
- PAK4
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Hintergrund
- PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
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Molekulargewicht
- 64 kDa
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Gen-ID
- 10298
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UniProt
- O96013
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Pathways
- RTK Signalweg
Target
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