NANOS3 Antikörper (AA 1-159)

Produktnummer ABIN7825582

Der Kaninchen Polyklonal Anti-NANOS3 Antikörper wurde für IHC validiert. Er ist geeignet, NANOS3 in Proben von Zebrafisch (Danio rerio) zu detektieren.

Kurzübersicht für NANOS3 Antikörper (AA 1-159) (ABIN7825582)

Target: NANOS3 (Nanos Homolog 3 (NANOS3))

Reaktivität: Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NANOS3 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktdetails anti-NANOS3 Antikörper

Bindungsspezifität: AA 1-159

Verwendungszweck: Anti-Zebrafish NANOS3 Antibody

Produktmerkmale: Anti-Zebrafish NANOS3 Antibody catalog #AZQ90WW1. Tested in IHC applications. This antibody reacts with Zebrafish.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived zebrafish NANOS3 recombinant protein (Position: M1-W159)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry, 2-5 μg/mL, Zebrafish

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu NANOS3

Target: NANOS3 (Nanos Homolog 3 (NANOS3))

Andere Bezeichnung: NANOS3

Hintergrund: Nanos is a zinc-finger containing, RNA-binding protein that has been implicated in germ cell development in both invertebrates and vertebrates. In Drosophila, Nanos represses apoptosis during development to ensure proper germ-line development. Unlike Nanos1 whose expression in mice is dispensable, the Nanos2 and Nanos3 proteins are required for germ cell development. Nanos2-null primordial germ cells (PGCs) die only in the male gonads and show no defects in females, while Nanos3-null PGCs are lost during the migration stage regardless of sex. Nanos2 and Nanos3 have distinct expression patterns during embryo development, suggesting that these two proteins do not have redundant functions. However, expression of Nanos2 can at least partially replace Nanos3 function in a Nanos3-null background. Nanos3 expression can not rescue Nanos2-null defects.

Pathways: ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Response to Molecule of Bacterial Origin, Myometrial Relaxation and Contraction, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling