GSTM2 Antikörper (Middle Region)
Kurzübersicht für GSTM2 Antikörper (Middle Region) (ABIN7825413)
Target
Alle GSTM2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- Middle Region
-
Verwendungszweck
- Anti-GSTM2 Antibody
-
Kreuzreaktivität (Details)
- No cross-reactivity with other proteins
-
Produktmerkmale
- Anti-GSTM2 Antibody (ABIN7825413). Tested in WB, IHC applications. This antibody reacts with Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
-
Aufreinigung
- Immunogen affinity purified.
-
Immunogen
- A synthetic peptide corresponding to a sequence in the middle region of mouse GSTM2. Human GSTM2 shares 95.5% amino acid (aa) sequence identity with rat GSTM2.
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
-
Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Immunohistochemistry, 2-5 μg/mL, Mouse
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Rekonstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
Konzentration
- 500 μg/mL
-
Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- GSTM2 (Glutathione S-Transferase mu 2 (Muscle) (GSTM2))
-
Andere Bezeichnung
- GSTM2
-
Hintergrund
- Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs.
-
Molekulargewicht
- 26 kDa
-
Gen-ID
- 14863
-
UniProt
- P15626
-
Pathways
- Negative Regulation of Transporter Activity
Target
-