Dieser Anti-GFRA2 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von GFRA2 in WB, ELISA, IHC, IF und FACS. Geeignet für Human, Maus und Ratte.
Produktnummer ABIN7825397
Kurzübersicht für GFRA2 Antikörper (AA 30-425) (ABIN7825397)
Anti-GFRA2 Antibody catalog # A06103-2. Tested in WB, IHC, IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
Aufreinigung
Immunogen affinity purified.
Immunogen
E.coli-derived human GFRA2 recombinant protein (Position: E30-L425). Human GFRA2 shares 97% amino acid (aa) sequence identity with mouse GFRA2.
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
Target
GFRA2
(GDNF Family Receptor alpha 2 (GFRA2))
Andere Bezeichnung
GFRA2
Hintergrund
Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene.