Frataxin Antikörper (AA 20-210)
Kurzübersicht für Frataxin Antikörper (AA 20-210) (ABIN7825383)
Target
Alle Frataxin (FXN) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 20-210
-
Verwendungszweck
- Anti-FXN Antibody
-
Kreuzreaktivität (Details)
- No cross-reactivity with other proteins
-
Produktmerkmale
- Anti-FXN Antibody catalog # A00842-1. Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
-
Aufreinigung
- Immunogen affinity purified.
-
Immunogen
- E.coli-derived human FXN recombinant protein (Position: Q20-A210). Human FXN shares 79% and 71.4% amino acid (aa) sequence identity with mouse and rat FXN, respectively.
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
-
Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry, 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Rekonstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
Konzentration
- 500 μg/mL
-
Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- Frataxin (FXN)
-
Andere Bezeichnung
- FXN
-
Hintergrund
- This nuclear gene encodes a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA from 8-33 repeats to >90 repeats results in Friedreich ataxia. Alternative splicing results in multiple transcript variants.
-
Molekulargewicht
- 14 kDa
-
Gen-ID
- 2395
-
UniProt
- Q16595
-
Pathways
- Transition Metal Ion Homeostasis, Regulation of Cell Size
Target
-