Frataxin Antikörper (FXN)

Details for Product anti-FXN Antibody No. ABIN6568875
Target
Reaktivität
Human, Maus, Ratte
96
28
16
4
4
4
3
3
2
2
1
1
1
1
Wirt
Kaninchen
83
22
Klonalität
Polyklonal
Konjugat
Dieser Frataxin Antikörper ist unkonjugiert
8
7
7
6
6
6
1
1
1
1
1
1
Applikation
Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
89
62
44
15
10
5
3
3
2
2
2
2
2
1
1
1
1
1
Optionen
Immunogen Recombinant protein of human FXN
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung FXN (FXN Antibody Abstract)
Hintergrund

Synonyms: CyaY,d-FXN,FA,FARR,Frataxin mature form,Frataxin(81-210),FRDA,FRDA,Friedreich ataxia protein,Fxn,i-FXN,m56-FXN,m78-FXN,m81-FXN,MGC57199,X25

Background: This nuclear gene encodes a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA from 8-33 repeats to >90 repeats results in Friedreich ataxia. Alternative splicing results in multiple transcript variants.

Molekulargewicht

Observed_MW: 14kDa

Calculated_MW: 19kDa/21kDa/23kDa

Gen-ID 2395
UniProt Q16595
Pathways Transition Metal Ion Homeostasis, Regulation of Cell Size
Applikations-hinweise WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Frataxin (FXN) antibody (ABIN6568875) Western blot analysis of extracts of various cell lines, using FXN antibody.
Image no. 2 for anti-Frataxin (FXN) antibody (ABIN6568875) Immunohistochemistry of paraffin-embedded rat heart using FXN antibody.
Image no. 3 for anti-Frataxin (FXN) antibody (ABIN6568875) Immunohistochemistry of paraffin-embedded mouse heart using FXN antibody.
Image no. 4 for anti-Frataxin (FXN) antibody (ABIN6568875) Immunofluorescence analysis of A549 cells using FXN antibody.