NCR3 Antikörper (PE-Cy7)

Produktnummer ABIN739993

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch NCR3 in FACS. Er zeigt eine Reaktivität gegenüber Human, Ratte und Hund.

Kurzübersicht für NCR3 Antikörper (PE-Cy7) (ABIN739993)

Target: NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))

Reaktivität: Human, Ratte, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NCR3 Antikörper ist konjugiert mit PE-Cy7

Applikation: Flow Cytometry (FACS)

Produktdetails anti-NCR3 Antikörper (PE-Cy7)

Kreuzreaktivität: Human

Homologie: Rat,Dog,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NCR3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu NCR3

Target: NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))

Andere Bezeichnung: NCR3

Hintergrund:

Synonyms: 1C7, MALS, CD337, LY117, NKp30, Natural cytotoxicity triggering receptor 3, Activating natural killer receptor p30, Natural killer cell p30-related protein, NK-p30, NCR3

Background: Cytotoxicity-activating receptor that contributes to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. Engagement of NCR3 by BAG6 also promotes dendritic cell (DC) maturation, both through killing those DCs that did not properly acquire a mature phenotype, and inducing NK cells to release TNFA and IFNG, which promotes DC maturation.

Molekulargewicht: 22kDa

Gen-ID: 259197

UniProt: O14931

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process