CAMLG Antikörper (Middle Region)

Produktnummer ABIN7825297

Der Kaninchen Polyklonal Anti-CAMLG Antikörper wurde für WB, IHC und FACS validiert. Er ist geeignet, CAMLG in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für CAMLG Antikörper (Middle Region) (ABIN7825297)

Target: CAMLG (Calcium Modulating Ligand (CAMLG))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CAMLG Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Produktdetails anti-CAMLG Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: Anti-CAMLG Antibody

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-CAMLG Antibody catalog # A08322-2. Tested in WB, IHC, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human CAMLG. Human CAMLG shares 91.7% and 95.7% amino acid (aa) sequence identity with mouse and rat CAMLG, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry, 2-5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu CAMLG

Target: CAMLG (Calcium Modulating Ligand (CAMLG))

Andere Bezeichnung: CAMLG

Hintergrund: The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin.

Molekulargewicht: 36 kDa

Gen-ID: 819

UniProt: P49069

Pathways: EGFR Signaling Pathway