NCR3 Antikörper (AA 81-180)

Produktnummer ABIN739980

Der Kaninchen Polyklonal anti-NCR3 Antikörper (ABIN739980) detektiert spezifisch NCR3 in ELISA, FACS und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für NCR3 Antikörper (AA 81-180) (ABIN739980)

Target: NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NCR3 Antikörper ist unkonjugiert

Applikation: ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-NCR3 Antikörper

Bindungsspezifität: AA 81-180

Kreuzreaktivität: Human

Homologie: Rat,Dog,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NCR3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu NCR3

Target: NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))

Andere Bezeichnung: NCR3

Hintergrund:

Synonyms: 1C7, MALS, CD337, LY117, NKp30, Natural cytotoxicity triggering receptor 3, Activating natural killer receptor p30, Natural killer cell p30-related protein, NK-p30, NCR3

Background: Cytotoxicity-activating receptor that contributes to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. Engagement of NCR3 by BAG6 also promotes dendritic cell (DC) maturation, both through killing those DCs that did not properly acquire a mature phenotype, and inducing NK cells to release TNFA and IFNG, which promotes DC maturation.

Gen-ID: 259197

UniProt: O14931

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process