Oct-2 Antikörper (AA 11-100)

Produktnummer ABIN737316

Dieses Anti-Oct-2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Oct-2 in WB, ELISA, IF (p), IHC (p), IF (cc) und IHC (fro). Geeignet für Human und Maus. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.

Kurzübersicht für Oct-2 Antikörper (AA 11-100) (ABIN737316)

Target: Oct-2 (POU2F2) (POU domain, class 2, transcription factor 2 (POU2F2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Oct-2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-Oct-2 Antikörper

Bindungsspezifität: AA 11-100

Kreuzreaktivität: Human, Maus

Homologie: Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse OCT2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-Oct-2 Antikörper (ABIN737316)

Zhou, Bi, Gao, An, Chen, Chen: "Macrophage polarization in human gingival tissue in response to periodontal disease." in: Oral diseases, Vol. 25, Issue 1, pp. 265-273, (2019) (PubMed).

Xu, Zhu, Chan, Lu, Shen, Gillies, Zhou: "The Altered Renal and Hepatic Expression of Solute Carrier Transporters (SLCs) in Type 1 Diabetic Mice." in: PLoS ONE, Vol. 10, Issue 3, pp. e0120760, (2015) (PubMed).

Details zu Oct-2

Target: Oct-2 (POU2F2) (POU domain, class 2, transcription factor 2 (POU2F2))

Andere Bezeichnung: 2-Oct

Hintergrund:

Synonyms: Otf2, Oct-2, Oct2a, Oct2b, Otf-2, POU domain, class 2, transcription factor 2, Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2, Octamer-binding protein 2, Octamer-binding transcription factor 2, Pou2f2, Oct2

Background: Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform OCT2.5 activates the U2 small nuclear RNA (snRNA) promoter. Isoforms OCT2.1, OCT2.2 and OCT2.3 activate octamer-containing promoters. Isoforms OCT2.4 and OCT2.5 repress some promoters and activate others. Isoform OCT2.7 is unable to bind to the octamer motif, but can still activate the beta-casein gene promoter at low levels.

Gen-ID: 18987

UniProt: Q00196