Rekombinanter Topo IIalpha (AA 650-700) Antikörper
Kurzübersicht für Rekombinanter Topo IIalpha (AA 650-700) Antikörper (ABIN7795794)
Target
Antikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 650-700
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Verwendungszweck
- Rabbit anti-Topo II Alpha Recombinant Monoclonal Antibody [BLR358N]
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Aufreinigung
- Purified
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Immunogen
- between 650 and 700
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Isotyp
- IgG
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Applikationshinweise
- ICC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.,IHC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.,WB,11,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 500 μg/mL
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Buffer
- Phosphate Buffered Saline (PBS) with 0.1 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- 2 - 8 °C
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Haltbarkeit
- 12 months
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- Topo IIalpha
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Andere Bezeichnung
- Topo II Alpha
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Hintergrund
- Topoisomerases regulate topological states of DNA and are divided into type I and type II enzymes. Type II topoisomerases make double stranded breaks in DNA and allow the passage of another duplex DNA across the break to achieve unknotting of entangled DNA. Topo II Alpha is one of two described isoforms that are likely products of a gene duplication event. TopoII Alpha is also described to be involved in chromosome condensation, chromatid separation, and the relief of supercoil stress.
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Gen-ID
- 7153
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UniProt
- P11388
Target
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