Rekombinanter Keratin 6 Antikörper (C-Term)

Produktnummer ABIN7795793

Dieser Kaninchen Monoklonal Antikörper erkennt spezifisch Keratin 6 in IHC, WB, ICC und IP. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Rekombinanter Keratin 6 Antikörper (C-Term) (ABIN7795793)

Target: Keratin 6 (KRT6)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Keratin 6 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Klon: BLR357N

Produktdetails anti-Keratin 6 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Rabbit anti-Cytokeratin 6 Recombinant Monoclonal Antibody [BLR357N] - BSA-Free

Aufreinigung: Purified

Immunogen: between 514 and 564 (C-term)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1000 μg/mL

Buffer: Phosphate Buffered Saline (PBS) with 0.09 % Sodium Azide, BSA-Free

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: 2 - 8 °C

Haltbarkeit: 12 months

Details zu Keratin 6

Target: Keratin 6 (KRT6)

Andere Bezeichnung: Cytokeratin 6

Hintergrund: Cytokeratins 5 and 6 are type II cytokeratins and consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. In normal tissue, Cyokeratin 5 is specifically expressed in the basal layer of the epidermis with family member KRT14 while Cytokeratin 6 is expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. Cytokeratins 5 and 6 are often referred to together as "CK5/6", and are commonly expressed in various cancers, particularly those originating from epithelial tissues, and their presence is often used as a marker to identify squamous cell carcinomas or tumors with a basal cell-like phenotype [taken from NCBI Entrez Gene (Gene ID: < a href="https://www.ncbi.nlm.nih.gov/gene/3852" class="gene-values" target="_blank">3852 and < a href="https://www.ncbi.nlm.nih.gov/gene/3853" class="gene-values" target="_blank">3853)].

Gen-ID: 3853

UniProt: P02538