PALB2
Reaktivität: Human
IHC
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
WB,11,000,IP,6 μL/mg lysate
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1000 μg/mL
Buffer
Phosphate Buffered Saline (PBS) with 0.09 % Sodium Azide, BSA-Free
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C
Informationen zur Lagerung
2 - 8 °C
Haltbarkeit
12 months
Target
PALB2
(Partner and Localizer of BRCA2 (PALB2))
Andere Bezeichnung
PALB2
Hintergrund
PALB2 (partner and localizer of BRCA2) interacts with BRCA2 and promotes BRCA2 localization and stability. PALB2 is also known as FANCN. Bi-allelic mutations in PALB2 result in Fanconi anemia disorder and breast cancer susceptibility. At the cellular level, PALB2 is important to the DNA damage response and chromosome stability and is essential to BRCA2 function.