Rekombinanter ARID1A Antikörper (AA 750-800)

Produktnummer ABIN7795677

Der Kaninchen Monoklonal anti-ARID1A Antikörper wird verwendet zum Nachweis von ARID1A in Proben von Human und Maus. Er wurde validiert für WB, IHC, ICC, FACS und IP.

Kurzübersicht für Rekombinanter ARID1A Antikörper (AA 750-800) (ABIN7795677)

Target: ARID1A (AT Rich Interactive Domain 1A (SWI-Like) (ARID1A))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser ARID1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunoprecipitation (IP)

Klon: BLR279L

Produktdetails anti-ARID1A Antikörper

Bindungsspezifität: AA 750-800

Verwendungszweck: Rabbit anti-ARID1A/BAF250 Recombinant Monoclonal Antibody [BLR279L]

Aufreinigung: Purified

Immunogen: Between 750 and 800

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow-Cyt,Fixed in 4 % formaldehyde and permeabilized with 90 % methanol. 1 μL per 1 x 10^6 cells.,ICC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.,IHC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.,IP,20 μL/mg lysate ,WB,11000 (3-8 % Tris-acetate gel recommended)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 50 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: 2 - 8 °C

Haltbarkeit: 12 months

Details zu ARID1A

Target: ARID1A (AT Rich Interactive Domain 1A (SWI-Like) (ARID1A))

Andere Bezeichnung: ARID1A/BAF250

Hintergrund: The SWI/SNF-related, matrix-associated, actin-dependent regulators of chromatin (SMARC), also called BRG1-associated factors (BAFs), have been identified as components of the human SWI/SNF-like chromatin-remodeling protein complexes. SWI/SNF complexes possess ATPase and DNA helicase activity that promotes transcriptional activation of genes normally repressed by chromatin structure. ARID1A/BAF250 is a noncatalytic subunit that is a member of the ARID (AT-rich interactive domain-containing protein) family of DNA binding proteins. ARID1A/BAF250 has been shown to play a role in the tumor suppressor activity of the SWI/SNF complexes. ARID1A/BAF250 is required for differentiation-associated cell cycle arrest.

Gen-ID: 8289

UniProt: O14497

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Tube Formation