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Rekombinanter CD22 (Epratuzumab Biosimilar) Antikörper

Der Humanized Monoklonal Anti-CD22 (Epratuzumab Biosimilar) Antikörper wurde für FACS und in vivo validiert. Er ist geeignet, CD22 (Epratuzumab Biosimilar) in Proben von Human zu detektieren.
Produktnummer ABIN7795107

Kurzübersicht für Rekombinanter CD22 (Epratuzumab Biosimilar) Antikörper (ABIN7795107)

Target

CD22 (Epratuzumab Biosimilar)

Antikörpertyp

Recombinant Antibody

Reaktivität

  • 4
  • 2
  • 2
Human

Wirt

  • 2
  • 1
  • 1
Humanized

Klonalität

  • 2
  • 2
Monoklonal

Konjugat

  • 4
Dieser CD22 (Epratuzumab Biosimilar) Antikörper ist unkonjugiert

Applikation

  • 3
  • 2
  • 2
  • 1
Flow Cytometry (FACS), In vivo Studies (in vivo)

Güteklasse

Research Grade
  • Expressionssystem

    Mammalian cells

    Verwendungszweck

    Epratuzumab Biosimilar, CD22 Monoclonal Antibody

    Produktmerkmale

    Epratuzumab Biosimilar uses the same protein sequences as the therapeutic antibody epratuzumab. Epratuzumab is a humanized monoclonal antibody derived from the murine IG2a monoclonal antibody, LL2 (EPB-2). This agent may subsequently be well matched for use in oncology and the treatment of inflammatory autoimmune disorders, such as lupus. Epratuzumab is a recombinant, humanized monoclonal antibody directed against CD22, a cell surface glycoprotein present on mature B-cells and on many types of malignant B-cells. It binds with high specificity to normal B-cells and B-cell tumors at the third Ig-like domain of CD22. After binding to CD22, epratuzumab's predominant antitumor activity appears to be mediated through antibody-dependent cellular cytotoxicity (ADCC).

    Aufreinigung

    Protein A or G affinity column

    Reinheit

    >95 % by reducing SDS-PAGE

    Endotoxin-Niveau

    < 1 EU per 1 mg of the protein by the LAL method

    Immunogen

    Human CD22
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    > 3 mg/mL

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.
  • Target

    CD22 (Epratuzumab Biosimilar)

    Andere Bezeichnung

    Epratuzumab Biosimilar

    Substanzklasse

    Biosimilar
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