Rekombinanter CD22 (Epratuzumab Biosimilar) Antikörper
Kurzübersicht für Rekombinanter CD22 (Epratuzumab Biosimilar) Antikörper (ABIN7795108)
Target
Antikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
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Expressionssystem
- Mammalian cells
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Verwendungszweck
- Epratuzumab Biosimilar, Endotoxin 0.05 EU/mg
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Produktmerkmale
- Epratuzumab Biosimilar uses the same protein sequences as the therapeutic antibody epratuzumab. Epratuzumab is a humanized monoclonal antibody derived from the murine IG2a monoclonal antibody, LL2 (EPB-2). This agent may subsequently be well matched for use in oncology and the treatment of inflammatory autoimmune disorders, such as lupus. Epratuzumab is a recombinant, humanized monoclonal antibody directed against CD22, a cell surface glycoprotein present on mature B-cells and on many types of malignant B-cells. It binds with high specificity to normal B-cells and B-cell tumors at the third Ig-like domain of CD22. After binding to CD22, epratuzumab's predominant antitumor activity appears to be mediated through antibody-dependent cellular cytotoxicity (ADCC).
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Aufreinigung
- Protein A or G affinity column
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Reinheit
- >95 % by reducing SDS-PAGE
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Endotoxin-Niveau
- Less than 0.5 EU/mg of protein as determined by LAL method
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Immunogen
- Human CD22
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- > 3 mg/mL
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.
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- CD22 (Epratuzumab Biosimilar)
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Andere Bezeichnung
- Epratuzumab Biosimilar
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Substanzklasse
- Biosimilar
Target
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