Cytokeratin 5 Antikörper (AA 331-430) (Cy7)

Produktnummer ABIN737067

Dieses Anti-Cytokeratin 5-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Cytokeratin 5 in WB, FACS, IF (cc) und IF (p). Geeignet für Human, Maus und Ratte.

Kurzübersicht für Cytokeratin 5 Antikörper (AA 331-430) (Cy7) (ABIN737067)

Target: Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cytokeratin 5 Antikörper ist konjugiert mit Cy7

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-Cytokeratin 5 Antikörper (Cy7)

Bindungsspezifität: AA 331-430

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CK5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Cytokeratin 5

Target: Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))

Andere Bezeichnung: Cytokeratin 5

Hintergrund:

Synonyms: Cytokeratin 5, Keratin, type II cytoskeletal 5, CK-5, CK 5, CK5, Keratin-5, K5, 58 kDa cytokeratin, KRT5, DDD, EBS 2, EBS2, K5, Keratin 5 epidermolysis bullosa simplex Dowling-Meara/Kobner/Weber-Cockayne types, Keratin 5, Keratin Type II Cytoskeletal 5, Keratin5, KRT 5, KRT 5A, KRT5, Cytokeratin-5, Cytokeratin5, DDD, epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types, K2C5_HUMAN, Keratin 5, Keratin, Keratin Type II Cytoskeletal 5, Keratin5, KRT5A, type II cytoskeletal 5, Type-II keratin Kb5.

Background: Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinising tissue (ie., skin) and non keratinising cells (ie., mesothelial cells). Although not a traditional marker for endothelial cells, cytokeratins have also been found in some microvascular endothelial cells. At least 20 different cytokeratins (CK) in the molecular range of 40 to 70 kDa and isoelectric points of 5 to 8.5 can be identified using two dimensional gel electrophoresis. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells. Defects in KRT5 are a cause of epidermolysis bullosa simplex.

Molekulargewicht: 64kDa

Gen-ID: 3852