HMGA1 Antikörper (AA 51-107)

Produktnummer ABIN736626

Dieses Anti-HMGA1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von HMGA1 in WB, ELISA, IF (cc), IF (p), IHC (p) und IHC (fro). Geeignet für Human und Maus. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für HMGA1 Antikörper (AA 51-107) (ABIN736626)

Target: HMGA1 (High Mobility Group AT-Hook 1 (HMGA1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HMGA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-HMGA1 Antikörper

Bindungsspezifität: AA 51-107

Kreuzreaktivität: Human, Maus

Homologie: Rat,Cow,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HMGA1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-HMGA1 Antikörper (ABIN736626)

Uchikura, Matsubara, Muto, Matsubara, Fujioka, Matsumoto, Sugiyama: "Extranuclear Translocation of High-Mobility Group A1 Reduces the Invasion of Extravillous Trophoblasts Involved in the Pathogenesis of Preeclampsia." in: Reproductive sciences (Thousand Oaks, Calif.), pp. 1933719117697250, (2017) (PubMed).

Details zu HMGA1

Target: HMGA1 (High Mobility Group AT-Hook 1 (HMGA1))

Andere Bezeichnung: HMGA1

Hintergrund:

Synonyms: HMG-R, HMGIY, HMGA1A, High mobility group protein HMG-I/HMG-Y, HMG-I(Y), High mobility group AT-hook protein 1, High mobility group protein A1, High mobility group protein R, HMGA1

Background: HMG-I/Y bind preferentially to the minor groove of A+T rich regions in double-stranded DNA. It is suggested that these proteins could function in nucleosome phasing and in the 3'-end processing of mRNA transcripts. They are also involved in the transcription regulation of genes containing, or in close proximity to A+T-rich regions.

Gen-ID: 3159

UniProt: P17096

Pathways: Nuclear Hormone Receptor Binding, Autophagie