IL-11 Antikörper (AA 22-120) (Cy7)

Produktnummer ABIN735029

Der Kaninchen Polyklonal Anti-IL-11-Antikörper wurde für WB, IF (cc) und IF (p) validiert. Er ist geeignet, IL-11 in Proben von Maus und Ratte zu detektieren.

Kurzübersicht für IL-11 Antikörper (AA 22-120) (Cy7) (ABIN735029)

Target: IL-11 (IL11) (Interleukin 11 (IL11))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL-11 Antikörper ist konjugiert mit Cy7

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-IL-11 Antikörper (Cy7)

Bindungsspezifität: AA 22-120

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Dog,Cow,Pig,Guinea Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IL-11

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu IL-11

Target: IL-11 (IL11) (Interleukin 11 (IL11))

Andere Bezeichnung: Il-11

Hintergrund:

Synonyms: Interleukin-11, Adipogenesis inhibitory factor, AG, IL 11, IL11, Interleukin 11, Oprelvekin, IL11_HUMAN.

Background: Interleukin 11 is a pleiotropic cytokine produced by mesenchymal-derived adherent cells. IL11 shares many functions of IL6 and LIF, including potentiation of megakaryocyte activity, enhancement of human myeloma cell proliferation, and enhancement of hepatic acute phase protein production.Interleukin 11 directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells, and induces megakaryocyte maturation resulting in increased platelet production. Clinically it is used to prevent severe thrombocytopenia and the reduction of the need for platelet transfusion following myelosuppressive chemotherapy.

Gen-ID: 3589

UniProt: P20809

Pathways: JAK-STAT Signalweg, Negative Regulation of Hormone Secretion