Neuregulin 1 Antikörper (AA 221-320) (Cy7)
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- Target Alle Neuregulin 1 (NRG1) Antikörper anzeigen
- Neuregulin 1 (NRG1)
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Bindungsspezifität
- AA 221-320
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Reaktivität
- Human, Ratte, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Neuregulin 1 Antikörper ist konjugiert mit Cy7
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Human, Maus, Ratte
- Homologie
- Dog,Chicken,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from mouse Pro-NRG1
- Isotyp
- IgG
- Top Product
- Discover our top product NRG1 Primärantikörper
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anti-Neuregulin 1 (NRG1) (AA 617-636), (C-Term) antibody
NRG1 Reaktivität: Human, Ratte WB, ICC, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Neuregulin 1 (NRG1) (C-Term) antibodyNRG1 Reaktivität: Human, Ratte, Maus WB, ICC, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Neuregulin 1 (NRG1) (N-Term) antibodyNRG1 Reaktivität: Human, Ratte, Maus WB, IHC, ELISA, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Neuregulin 1 (NRG1) (AA 198-229) antibodyNRG1 Reaktivität: Human WB, IHC, ELISA, FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Neuregulin 1 (NRG1) (AA 221-320) antibodyNRG1 Reaktivität: Human, Ratte, Maus WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Neuregulin 1 (NRG1) (AA 198-229) antibodyNRG1 Reaktivität: Human FACS, IHC (p) Wirt: Kaninchen Polyclonal RB01275-01276 unconjugated
anti-Neuregulin 1 (NRG1) (AA 1-241) antibodyNRG1 Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Neuregulin 1 (NRG1) (AA 21-242) antibodyNRG1 Reaktivität: Human IHC, StM Wirt: Maus Monoclonal NRG1-2710 unconjugated
anti-Neuregulin 1 (NRG1) antibodyNRG1 Reaktivität: Human WB, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Neuregulin 1 (NRG1) (AA 21-242) antibodyNRG1 Reaktivität: Human ELISA, IF, Coat Wirt: Maus Monoclonal NRG1-2752 unconjugated
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- Applikationshinweise
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- Neuregulin 1 (NRG1)
- Andere Bezeichnung
- Pro-NRG1 (NRG1 Produkte)
- Hintergrund
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Synonyms: GGF, HGL, HRG, NDF, ARIA, GGF2, HRG1, HRGA, SMDF, MST131, MSTP131, NRG1-IT2, Pro-neuregulin-1, membrane-bound isoform, Pro-NRG1, NRG1
Background: Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. The multiple isoforms perform diverse functions such as inducing growth and differentiation of epithelial, glial, neuronal, and skeletal muscle cells, inducing expression of acetylcholine receptor in synaptic vesicles during the formation of the neuromuscular junction, stimulating lobuloalveolar budding and milk production in the mammary gland and inducing differentiation of mammary tumor cells, stimulating Schwann cell proliferation, implication in the development of the myocardium such as trabeculation of the developing heart. Isoform 10 may play a role in motor and sensory neuron development.
- Gen-ID
- 211323
- UniProt
- Q6DR98
- Pathways
- RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Muscle Cell Differentiation
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