Transferrin Receptor Antikörper (AA 21-120)

Produktnummer ABIN734378

Der Kaninchen Polyklonal Anti-Transferrin Receptor-Antikörper wurde für FACS und ELISA validiert. Er ist geeignet, Transferrin Receptor in Proben von Human zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für Transferrin Receptor Antikörper (AA 21-120) (ABIN734378)

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Transferrin Receptor Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), ELISA

Produktdetails anti-Transferrin Receptor Antikörper

Bindungsspezifität: AA 21-120

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Cow,Pig,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Transferrin receptor

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-Transferrin Receptor Antikörper (ABIN734378)

Gao, Bai, Wang, Sun, Guan, Zheng: "All-trans retinoic acid promotes nerve cell differentiation of yolk sac-derived mesenchymal stem cells." in: Applied biochemistry and biotechnology, Vol. 174, Issue 2, pp. 682-92, (2014) (PubMed).

Gao, Bai, Xiong, Li, Shan, Huang, Ma, Guan: "Isolation and characterization of chicken dermis-derived mesenchymal stem/progenitor cells." in: BioMed research international, Vol. 2013, pp. 626258, (2013) (PubMed).

Details zu Transferrin Receptor

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Andere Bezeichnung: Transferrin receptor

Hintergrund:

Synonyms: Transferrin receptor protein 1, TR, TfR, TfR1, Trfr, T9, p90, TFRC

Background: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site.

Molekulargewicht: 95kDa

Gen-ID: 7037

UniProt: P02786

Pathways: Transition Metal Ion Homeostasis