Endoglin Antikörper (FineTest®700)

Produktnummer ABIN7675479

Dieser Ratte Monoklonal Antikörper erkennt spezifisch Endoglin in FACS. Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für Endoglin Antikörper (FineTest®700) (ABIN7675479)

Target: Endoglin (ENG)

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser Endoglin Antikörper ist konjugiert mit FineTest®700

Applikation: Flow Cytometry (FACS)

Klon: MJ7-18

Produktdetails anti-Endoglin Antikörper (FineTest®700)

Verwendungszweck: FineTest®700 Anti-Mouse CD105 Antibody

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0. 1 % sodium azide, 1 %BSA, pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu Endoglin

Target: Endoglin (ENG)

Andere Bezeichnung: CD105

Hintergrund:

Synonyms: END|Endoglin|Eng

Background: CD105 is a 90 kD homodimeric type I integral membrane glycoprotein, also known as endoglin. It is expressed on endothelial cells (especially on angiogenic endothelial cells) and upregulated by hypoxia, activated monocytes, macrophages, bone marrow stromal cells, and some cytotrophoblasts. CD105 is a receptor for TGF-β1, TGF-β3 and modulates TGF-β signaling by interacting with TGF-β receptors I and/or II. CD105 also binds other growth factors such as actvin A, BMP-2, and BMP-7. CD105 has been show to be a useful marker for identifying proliferating endothelium involved in tumor angiogenesis and can be used for tumor imaging and prognosis, and has therapeutic potential for some solid tumors and other angiogenic diseases.

Molekulargewicht: 0

Gen-ID: 13805

UniProt: Q63961