CD80 Antikörper (PerCP-Cy5.5)

Produktnummer ABIN7674334

Dieses Anti-CD80-Antikörper ist ein Armenischer Hamster Monoklonal-Antikörper zur Detektion von CD80 in FACS. Geeignet für Maus.

Kurzübersicht für CD80 Antikörper (PerCP-Cy5.5) (ABIN7674334)

Target: CD80

Reaktivität: Maus

Wirt: Armenischer Hamster

Klonalität: Monoklonal

Konjugat: Dieser CD80 Antikörper ist konjugiert mit PerCP-Cy5.5

Applikation: Flow Cytometry (FACS)

Klon: 16-10A1

Produktdetails anti-CD80 Antikörper (PerCP-Cy5.5)

Verwendungszweck: PerCP-Cy5.5 Anti-Mouse CD80 Antibody

Aufreinigung: 0

Reinheit: 0

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu CD80

Target: CD80

Andere Bezeichnung: CD80

Hintergrund:

Synonyms: Activation B7-1 antigen|B7|Cd80|T-lymphocyte activation antigen CD80

Background: CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

Molekulargewicht: 0

Gen-ID: 12519

UniProt: Q00609

Pathways: T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints