LAMP1 Antikörper (PerCP-Cy5.5)

Produktnummer ABIN7674301

Dieses Anti-LAMP1-Antikörper ist ein Ratte Monoklonal-Antikörper zur Detektion von LAMP1 in FACS. Geeignet für Maus.

Kurzübersicht für LAMP1 Antikörper (PerCP-Cy5.5) (ABIN7674301)

Target: LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser LAMP1 Antikörper ist konjugiert mit PerCP-Cy5.5

Applikation: Flow Cytometry (FACS)

Klon: 1D4B

Produktdetails anti-LAMP1 Antikörper (PerCP-Cy5.5)

Verwendungszweck: PerCP-Cy5.5 Anti-Mouse CD107a Antibody

Aufreinigung: 0

Reinheit: 0

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu LAMP1

Target: LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

Andere Bezeichnung: CD107a

Hintergrund:

Synonyms: CD107 antigen-like family member Alysosomal membrane glycoprotein 1lysosome-associated membrane protein 1|LAMP-1|Lysosome-associated membrane glycoprotein 1|LAMP-1

Background: The 1D4B antibody recognizes CD107a which is also known as, Lysosome-Associated Membrane Protein 1 (LAMP-1). CD107a is one of the two major glycoproteins in lysosome membranes that provide useful markers to distinguish lysosomes from other organelles. CD107a may play a role in the lysosomal degradation of certain molecules. Mouse CD107a is a type I transmembrane glycoprotein. It consists of a 40- kDa core protein which is heavily glycosylated to form heterogeneous mature glycoprotein of 110-140 kDa.  It is principally expressed in epithelial cells and macrophages in a variety of organs. Following activation, CD107a is relocated to the surface of some lymphocytes, macrophages, epithelial cells, endothelial cells, platelets, and tumor cells. Cell-surface CD107a may participate in intercellular adhesion and adhesion to the extracellular matrix. Cell surface CD107a expression can serve as a useful marker for cytotoxic NK and CD8+ T cells, as well as, some malignant tumor cells.

Molekulargewicht: 0

Gen-ID: 16783

UniProt: P11438

Pathways: Autophagie