CD55 Antikörper (PerCP-Cy5.5)
Kurzübersicht für CD55 Antikörper (PerCP-Cy5.5) (ABIN7674277)
Target
Alle CD55 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- PerCP-Cy5.5 Anti-Human CD55 Antibody
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Aufreinigung
- 0
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Reinheit
- 0
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Isotyp
- IgG2a, kappa
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Applikationshinweise
- Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)
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Haltbarkeit
- 12 months
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- CD55 (Complement Decay-Accelerating Factor (CD55))
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Andere Bezeichnung
- CD55
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Hintergrund
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Synonyms: Complement decay-accelerating factor|CD55|CR|DAF
Background: CD55 is a 60-70 kD glycosylphosphatidylinositol (GPI)-anchored single chain glycoprotein also known as decay-accelerating factor (DAF). It is expressed on hematopoietic cells including erythrocytes and many non-hematopoietic cells. CD55 accelerates the dissociation of the components of the C3-convertases (namely C2a from C4b in the C4bC2a complex, a C3-convertase of the classical pathway, and factor Bb from the C3bBb complex, a C3-convertase of the alternative pathway) to protect cells from inappropriate damage caused by autologous complement. CD55 has been reported to reduce the efficiency of NK cell lysis and induce signal transduction in T cells. CD55 has also been shown to interact with CD97 and bind to Coxsackie and Echovirus.
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Molekulargewicht
- 0
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Gen-ID
- 1604
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UniProt
- P08174
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Pathways
- Komplementsystem, Regulation of Leukocyte Mediated Immunity
Target
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