CD86 Antikörper (PE-Cy5.5)

Produktnummer ABIN7673982

Der Ratte Monoklonal Anti-CD86-Antikörper wurde für FACS validiert. Er ist geeignet, CD86 in Proben von Maus zu detektieren.

Kurzübersicht für CD86 Antikörper (PE-Cy5.5) (ABIN7673982)

Target: CD86

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser CD86 Antikörper ist konjugiert mit PE-Cy5.5

Applikation: Flow Cytometry (FACS)

Klon: GL-1

Produktdetails anti-CD86 Antikörper (PE-Cy5.5)

Verwendungszweck: PE-Cy5.5 Anti-Mouse CD86 Antibody

Aufreinigung: 0

Reinheit: 0

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu CD86

Target: CD86

Andere Bezeichnung: CD86

Hintergrund:

Synonyms: Activation B7-2 antigen|Cd86|ETC-1|Early T-cell costimulatory molecule 1|T-lymphocyte activation antigen CD86

Background: CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is a ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce co-stimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

Molekulargewicht: 0

Gen-ID: 12524

UniProt: P42082

Pathways: T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation