IL2 Receptor beta Antikörper (PE-Cy5)

Produktnummer ABIN7673865

Der Ratte Monoklonal Anti-IL2 Receptor beta-Antikörper wurde für FACS validiert. Er ist geeignet, IL2 Receptor beta in Proben von Maus zu detektieren.

Kurzübersicht für IL2 Receptor beta Antikörper (PE-Cy5) (ABIN7673865)

Target: IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser IL2 Receptor beta Antikörper ist konjugiert mit PE-Cy5

Applikation: Flow Cytometry (FACS)

Klon: 5H4

Produktdetails anti-IL2 Receptor beta Antikörper (PE-Cy5)

Verwendungszweck: PE-Cy5 Anti-Mouse CD122/IL-2RB Antibody

Aufreinigung: 0

Reinheit: 0

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu IL2 Receptor beta

Target: IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

Andere Bezeichnung: CD122

Hintergrund:

Synonyms: IL-2R subunit beta|CD122|High affinity IL-2 receptor subunit beta|IL-2 receptor subunit beta|IL-2RB|Il2rb|Interleukin-2 receptor subunit beta|p70-75

Background: CD122 is a 70-75 kD IL-2 receptor β chain also known as IL-2Rβ, which is also shared by the IL-15 receptor. It is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL-2Rβ chain can combine with either the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation. The 5H4 antibody does not block IL-2 binding to the IL-2 receptor. CD122 is expressed on murine, but not human, CD8+ Tregs involved in the maintenance of T cell homeostasis.

Molekulargewicht: 0

Gen-ID: 16185

UniProt: P16297

Pathways: JAK-STAT Signalweg, Growth Factor Binding