Mesothelin Antikörper

Produktnummer ABIN7673469

Der Kaninchen Polyklonal anti-Mesothelin Antikörper wird verwendet zum Nachweis von Mesothelin in Proben von Human. Er wurde validiert für WB, ELISA und IHC.

Kurzübersicht für Mesothelin Antikörper (ABIN7673469)

Target: Mesothelin (MSLN)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Mesothelin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-Mesothelin Antikörper

Verwendungszweck: MSLN antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: Mesothelin

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000, IHC: 1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu Mesothelin

Target: Mesothelin (MSLN)

Andere Bezeichnung: MSLN

Hintergrund:

Synonyms: Mesothelin|CAK1 antigen|Pre-pro-megakaryocyte-potentiating factor|Megakaryocyte-potentiating factor (MPF)|Mesothelin, cleaved form|MSLN|MPF

Background: Mesothelin (MSLN) is a 40 kDa GPI-anchored surface glycoprotein that is expressed on pleural and peritoneal mesothelial cells, but not in other non-neoplastic tissues. The mesothelin gene encodes a 69-71 kDa precursor protein that is processed to a 40 kDa membrane-bound protein termed mesothelin and a 31 kDa shed fragment called megakaryocyte-potentiating factor (MPF) that is released from the cell.

Molekulargewicht: 70 kDa, 40 kDa

Gen-ID: 10232

UniProt: Q13421

Pathways: EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process