SIRPA Antikörper (FITC)

Produktnummer ABIN7673203

Dieses Anti-SIRPA-Antikörper ist ein Ratte Monoklonal-Antikörper zur Detektion von SIRPA in FACS. Geeignet für Maus.

Kurzübersicht für SIRPA Antikörper (FITC) (ABIN7673203)

Target: SIRPA (Signal-Regulatory Protein alpha (SIRPA))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser SIRPA Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS)

Klon: P84

Produktdetails anti-SIRPA Antikörper (FITC)

Verwendungszweck: FITC Anti-Mouse CD172a/SIRPα Antibody

Aufreinigung: 0

Reinheit: 0

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu SIRPA

Target: SIRPA (Signal-Regulatory Protein alpha (SIRPA))

Andere Bezeichnung: CD172a

Hintergrund:

Synonyms: BIT|CD172 antigen-like family member A|P84|PTPNS1|SHPS-1|SIRPα

Background: CD172a, also known as SIRPα, is a type I transmembrane protein with one V-set Ig-like and two C-set Ig-like domains in the extracellular portion, and two ITIM motifs and a proline-rich region in the cytoplasmic tail. CD172a is expressed by monocytes, macrophages, myeloid cells, and neuronal tissue. The phosphorylation of SIRPα ITIMs induces the recruitment and activation of the tyrosine phosphatases PTPN6 and PTPN11, resulting in the negative regulation of several biological processes. The ligands of CD172a are CD47, SP-A, and SP-D.

Molekulargewicht: 0

Gen-ID: 19261

UniProt: P97797