Cyclin E2 Antikörper

Produktnummer ABIN7672945

Dieses Anti-Cyclin E2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Cyclin E2 in WB, ELISA und IF. Geeignet für Human, Maus und Ratte.

Kurzübersicht für Cyclin E2 Antikörper (ABIN7672945)

Target: Cyclin E2 (CCNE2)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cyclin E2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-Cyclin E2 Antikörper

Verwendungszweck: CCNE2 antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: G1/S-specific cyclin-E2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000, IF: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu Cyclin E2

Target: Cyclin E2 (CCNE2)

Andere Bezeichnung: CCNE2

Hintergrund:

Synonyms: G1/S-specific cyclin-E2|CCNE2

Background: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2. This cyclin has been shown to specifically interact with CIP/KIP family of CDK inhibitors, and plays a role in cell cycle G1/S transition. The expression of this gene peaks at the G1-S phase and exhibits a pattern of tissue specificity distinct from that of cyclin E1. A significantly increased expression level of this gene was observed in tumor-derived cells.

Molekulargewicht: 44 kDa

Gen-ID: 9134

UniProt: O96020

Pathways: Zellzyklus, Mitotic G1-G1/S Phases