Liver Arginase Antikörper

Produktnummer ABIN7672893

Der Kaninchen-Polyklonal Anti-Liver Arginase-Antikörper wurde für WB, ELISA und IF validiert. Er ist geeignet zum Nachweis von Liver Arginase in Proben aus Human, Ratte und Maus. }

Kurzübersicht für Liver Arginase Antikörper (ABIN7672893)

Target: Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Liver Arginase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-Liver Arginase Antikörper

Verwendungszweck: ARG1 antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: arginase, liver

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000, IF: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu Liver Arginase

Target: Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Andere Bezeichnung: ARG1

Hintergrund:

Synonyms: Arginase-1|Liver-type arginase|Type I arginase|ARG1

Background: Arginase-1(Liver arginase) belongs to the arginase family. ARG1 is a novel immunohistochemicalmarkerof hepatocellular differentiation in fine needle aspiration cytology and a markerof hepatocytes and hepatocellular neoplasms. ARG1 is closely associated with alternative macrophage activation(PMID:12098359) and ARG1 has been shown to protectmotor neurons from trophic factor deprivation and allow sensory neurons to overcome neurite outgrowth inhibition by myelin proteins(PMID: 20071539).It can exsit as a homotrimer(PMID:16141327) and it has 3 isoforms produced by alternative splicing.Defects in ARG1 are the cause of argininemia(ARGIN). Deletion or TNF-mediated restriction of ARG1 unleashes the production of NO by NOS2, which is critical for pathogen control.(PMID:27117406).

Molekulargewicht: 25-40 kDa

Gen-ID: 383

UniProt: P05089

Pathways: Cellular Response to Molecule of Bacterial Origin