CD180 Antikörper (APC)

Produktnummer ABIN7672668

Der Maus Monoklonal Anti-CD180-Antikörper wurde für FACS validiert. Er ist geeignet, CD180 in Proben von Human zu detektieren.

Kurzübersicht für CD180 Antikörper (APC) (ABIN7672668)

Target: CD180 (CD180 Molecule (CD180))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD180 Antikörper ist konjugiert mit APC

Applikation: Flow Cytometry (FACS)

Klon: MHR73-11

Produktdetails anti-CD180 Antikörper (APC)

Verwendungszweck: APC Anti-Human CD180 Antibody

Aufreinigung: 0

Reinheit: 0

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu CD180

Target: CD180 (CD180 Molecule (CD180))

Andere Bezeichnung: CD180

Hintergrund:

Synonyms: CD180|Radio-protective 105-kD protein|RP105

Background: CD180, also known as RP105, is a 105 kD member of the toll-like receptor (TLR) family and is expressed on most B cells, monocytes/macrophages and dendritic cells. The TLR family's structural characteristics are critically involved in protein-protein signaling interactions leading to the activation of the innate immune system. Additionally, MD-1, a secretory protein, associates with CD180 (RP105) at the cell surface and this complex, in conjunction with TLR4, recognizes bacterial LPS. The human CD180 (RP105) gene maps to 5q12. The MHR73-11 antibody is able to activate B cells and to protect against irradiation- or dexamethasone-induced apoptosis.

Molekulargewicht: 0

Gen-ID: 4064

UniProt: Q99467

Pathways: Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades