VCAM1 Antikörper

Produktnummer ABIN7670763

Der Kaninchen Polyklonal Anti-VCAM1-Antikörper wurde für WB, IHC und ELISA validiert. Er ist geeignet, VCAM1 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für VCAM1 Antikörper (ABIN7670763)

Target: VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VCAM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-VCAM1 Antikörper

Verwendungszweck: VCAM-1/CD106 Polyclonal Antibody(Capture/Detector)

Aufreinigung: Antigen Affinity Purification

Immunogen: Recombinant Rat VCAM-1/CD106 protein expressed by Mammalian

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000,IHC 1:1000-1:2000,ELISA Capture 2-8 μg/mL,ELISA Detector 0.1-0.4 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Sterile PBS , pH 7.4

Konservierungsmittel: Without preservative

Handhabung: Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C Valid for 1 month or -20°C Valid for 12 months

Haltbarkeit: 12 months

Details zu VCAM1

Target: VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

Andere Bezeichnung: VCAM-1/CD106

Hintergrund: CD106,Vcam1,Vcam-1,V-CAM 1,VascuLar ceLL adhesion protein 1,SoLubLe VascuLar CeLL Adhesion MoLecuLe-1,Cell adhesion glycoprotein predominantly expressed on the surface of endothelial cells that plays an important role in immune surveillance and inflammation. Acts as a major regulator of leukocyte adhesion to the endothelium through interaction with different types of integrins. During inflammatory responses,binds ligands on the surface of activated endothelial cells to initiate the activation of calcium channels and the plasma membrane-associated small GTPase RAC1 leading to leukocyte transendothelial migration. Serves also as a quality-control checkpoint for entry into bone marrow by providing a 'don't-eat-me' stamping in the context of major histocompatibility complex (MHC) class-I presentation.

Molekulargewicht:

Calculated MW: 81kDa

ObservedMW: 75-100kDa

UniProt: P29534

Pathways: Carbohydrate Homeostasis