Ret Proto-Oncogene Antikörper

Produktnummer ABIN7670736

Der Kaninchen Polyklonal Anti-Ret Proto-Oncogene-Antikörper wurde für ELISA validiert. Er ist geeignet, Ret Proto-Oncogene in Proben von Human zu detektieren.

Kurzübersicht für Ret Proto-Oncogene Antikörper (ABIN7670736)

Target: Ret Proto-Oncogene (RET)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Ret Proto-Oncogene Antikörper ist unkonjugiert

Applikation: ELISA

Produktdetails anti-Ret Proto-Oncogene Antikörper

Verwendungszweck: RET Polyclonal Antibody(Capture/Detector)

Aufreinigung: Antigen Affinity Purification

Immunogen: Recombinant Human RET protein expressed by Mammalian

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA Capture 2-8 μg/mL,ELISA Detector 0.1-0.4 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Sterile PBS , pH 7.4

Konservierungsmittel: Without preservative

Handhabung: Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C Valid for 1 month or -20°C Valid for 12 months

Haltbarkeit: 12 months

Details zu Ret Proto-Oncogene

Target: Ret Proto-Oncogene (RET)

Andere Bezeichnung: RET

Hintergrund: Proto-oncogene tyrosine-protein kinase receptor Ret,Cadherin family member 12,Proto-oncogene c-Ret,This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed. RET (Ret Proto-Oncogene) is a Protein Coding gene. Diseases associated with RET include Multiple Endocrine Neoplasia Iia and Medullary Thyroid Carcinoma, Familial. Among its related pathways are RET signaling and Innate Immune System. GO annotations related to this gene include calcium ion binding and protein kinase activity. An important paralog of this gene is PDGFRB.

UniProt: P07949

Pathways: RTK Signalweg, Dopaminergic Neurogenesis, Regulation of Cell Size, Tube Formation