PLAU Antikörper

Produktnummer ABIN7670721

Der Ratte Monoklonal Anti-PLAU-Antikörper wurde für ELISA (Detection) validiert. Er ist geeignet, PLAU in Proben von Human zu detektieren.

Kurzübersicht für PLAU Antikörper (ABIN7670721)

Target: PLAU (Plasminogen Activator, Urokinase (PLAU))

Reaktivität: Human

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser PLAU Antikörper ist unkonjugiert

Applikation: ELISA (Detection)

Klon: 9B8

Produktdetails anti-PLAU Antikörper

Verwendungszweck: Plasminogen Activator/Urokinase Monoclonal Antibody(Detector)

Aufreinigung: Protein A/G Purification

Immunogen: Recombinant Human Plasminogen Activator/Urokinase protein expressed by Mammalian

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA Detector 0.1-0.4 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Sterile PBS , pH 7.4

Konservierungsmittel: Without preservative

Handhabung: Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C Valid for 1 month or -20°C Valid for 12 months

Haltbarkeit: 12 months

Details zu PLAU

Target: PLAU (Plasminogen Activator, Urokinase (PLAU))

Andere Bezeichnung: Plasminogen Activator/Urokinase

Hintergrund: UPA,u-PA,ATF,URK,UP-A,Urokinase,Abbokinase,This gene encodes a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and proliferation. A specific polymorphism in this gene may be associated with late-onset Alzheimer's disease and also with decreased affinity for fibrin-binding. This protein converts plasminogen to plasmin by specific cleavage of an Arg-Val bond in plasminogen. Plasmin in turn cleaves this protein at a Lys-Ile bond to form a two-chain derivative in which a single disulfide bond connects the amino-terminal A-chain to the catalytically active, carboxy-terminal B-chain. This two-chain derivative is also called HMW-uPA (high molecular weight uPA). HMW-uPA can be further processed into LMW-uPA (low molecular weight uPA) by cleavage of chain A into a short chain A (A1) and an amino-terminal fragment. LMW-uPA is proteolytically active but does not bind to the uPA receptor. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

UniProt: P00749

Pathways: Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagie, Smooth Muscle Cell Migration