Leptin Receptor Antikörper

Produktnummer ABIN7670679

Der Kaninchen Polyklonal Anti-Leptin Receptor-Antikörper wurde für ELISA validiert. Er ist geeignet, Leptin Receptor in Proben von Maus zu detektieren.

Kurzübersicht für Leptin Receptor Antikörper (ABIN7670679)

Target: Leptin Receptor (LEPR)

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Leptin Receptor Antikörper ist unkonjugiert

Applikation: ELISA

Produktdetails anti-Leptin Receptor Antikörper

Verwendungszweck: Leptin R Polyclonal Antibody(Capture/Detector)

Aufreinigung: Antigen Affinity Purification

Immunogen: Recombinant Mouse Leptin R protein expressed by Mammalian

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA Capture 2-8 μg/mL,ELISA Detector 0.1-0.4 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Sterile PBS , pH 7.4

Konservierungsmittel: Without preservative

Handhabung: Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C Valid for 1 month or -20°C Valid for 12 months

Haltbarkeit: 12 months

Details zu Leptin Receptor

Target: Leptin Receptor (LEPR)

Andere Bezeichnung: Leptin R

Hintergrund: CD295,LEP-R,LR,LEPRD,OB-R,OBR,The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).

UniProt: P48356

Pathways: JAK-STAT Signalweg, AMPK Signaling, Feeding Behaviour