HMOX1 Antikörper

Produktnummer ABIN7670621

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch HMOX1 in WB, IHC und ELISA. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für HMOX1 Antikörper (ABIN7670621)

Target: HMOX1 (Heme Oxygenase (Decycling) 1 (HMOX1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HMOX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-HMOX1 Antikörper

Verwendungszweck: HO1/HMOX1 Polyclonal Antibody

Aufreinigung: Antigen Affinity Purification

Immunogen: Recombinant Human HO1/HMOX1 protein expressed by E.coli

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000,IHC 1:500-1:1000,ELISA Capture 2-8 μg/mL,ELISA Detector 0.1-0.4 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Sterile PBS , pH 7.4

Konservierungsmittel: Without preservative

Handhabung: Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C Valid for 1 month or -20°C Valid for 12 months

Haltbarkeit: 12 months

Details zu HMOX1

Target: HMOX1 (Heme Oxygenase (Decycling) 1 (HMOX1))

Andere Bezeichnung: HO1/HMOX1

Hintergrund: Heme oxygenase 1,HO-1,HMOX1,HO,HO1,EC:1.14.14.18,Heme Oxygenase (HO),also known as HMOX,is the rate limiting enzyme in the breakdown of heme into Biliverdin,CO,and iron. There are two major isoforms of this enzyme,HO-1 and HO-2. Both have similar enzymatic activity,however,HO-1 is rapidly inducible,while HO-2 is constitutively expressed. Inducers of HO-1 include cell stressors such as oxidative stress,infection,hypoxia,and cytotoxic agents. The reaction products generated by HO-1 activity are biologically active,and the enzyme has a broad range of putative roles. For instance,Biliverdin is an antioxidant with cytoprotective and anti-inflammatory properties,and CO has the potential to suppress inflammation and apoptosis. Because of these activities,HO-1 has received much attention as a therapeutic target for a range of pathological processes.

Molekulargewicht:

Calculated MW: 33kDa

ObservedMW: 25kDa

UniProt: P09601

Pathways: Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, SARS-CoV-2 Protein Interaktom