HMOX1 Antikörper

Produktnummer ABIN7670621

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch HMOX1 in WB, IHC und ELISA. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für HMOX1 Antikörper (ABIN7670621)

Target: HMOX1 (Heme Oxygenase (Decycling) 1 (HMOX1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HMOX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-HMOX1 Antikörper

Verwendungszweck: HO1/HMOX1 Polyclonal Antibody

Aufreinigung: Antigen Affinity Purification

Immunogen: Recombinant Human HO1/HMOX1 protein expressed by E.coli

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000,IHC 1:500-1:1000,ELISA Capture 2-8 μg/mL,ELISA Detector 0.1-0.4 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Sterile PBS , pH 7.4

Konservierungsmittel: Without preservative

Handhabung: Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C Valid for 1 month or -20°C Valid for 12 months

Haltbarkeit: 12 months

Details zu HMOX1

Target: HMOX1 (Heme Oxygenase (Decycling) 1 (HMOX1))

Andere Bezeichnung: HO1/HMOX1

Hintergrund: Heme oxygenase 1,HO-1,HMOX1,HO,HO1,EC:1.14.14.18,Heme Oxygenase (HO),also known as HMOX,is the rate limiting enzyme in the breakdown of heme into Biliverdin,CO,and iron. There are two major isoforms of this enzyme,HO-1 and HO-2. Both have similar enzymatic activity,however,HO-1 is rapidly inducible,while HO-2 is constitutively expressed. Inducers of HO-1 include cell stressors such as oxidative stress,infection,hypoxia,and cytotoxic agents. The reaction products generated by HO-1 activity are biologically active,and the enzyme has a broad range of putative roles. For instance,Biliverdin is an antioxidant with cytoprotective and anti-inflammatory properties,and CO has the potential to suppress inflammation and apoptosis. Because of these activities,HO-1 has received much attention as a therapeutic target for a range of pathological processes.

Molekulargewicht:

Calculated MW: 33kDa

ObservedMW: 25kDa

UniProt: P09601

Pathways: Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, SARS-CoV-2 Protein Interaktom