Galectin 3 Antikörper

Produktnummer ABIN7670615

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Galectin 3 in IHC, ELISA und IF. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für Galectin 3 Antikörper (ABIN7670615)

Target: Galectin 3 (LGALS3)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Galectin 3 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-Galectin 3 Antikörper

Verwendungszweck: Galectin-3 Polyclonal Antibody

Aufreinigung: Antigen Affinity Purification

Immunogen: Recombinant Human Galectin-3 protein expressed by E.coli

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:650-1:1250,IF 1:50-1:200,ELISA Capture 2-8 μg/mL,ELISA Detector 0.1-0.4 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Sterile PBS , pH 7.4

Konservierungsmittel: Without preservative

Handhabung: Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C Valid for 1 month or -20°C Valid for 12 months

Haltbarkeit: 12 months

Details zu Galectin 3

Target: Galectin 3 (LGALS3)

Andere Bezeichnung: Galectin-3

Hintergrund: GAL3,GaL-3,GaLectin-3,35 kDa Lectin,Carbohydrate-binding protein 35 (CBP 35),GaLactose-specific Lectin 3,GaLactoside-binding protein (GALBP),IgE-binding protein,LGALS3,MAC2,Galactose-specific lectin which binds IgE. May mediate with the alpha-3,beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1,required for terminal differentiation of columnar epithelial cells during early embryogenesis.In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion,chemoattraction of monocytes macrophages,opsonization of apoptotic neutrophils,and activation of mast cells. Together with TRIM16,coordinates the recognition of membrane damage with mobilization of the core autophagy regulators ATG16l1 and BECN1 in response to damaged endomembranes.

UniProt: P17931

Pathways: RTK Signalweg