EPO Antikörper

Produktnummer ABIN7670597

Dieses Ratte Monoklonal-Antikörper erkennt spezifisch EPO in ELISA (Detection). Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für EPO Antikörper (ABIN7670597)

Target: EPO (Erythropoietin (EPO))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser EPO Antikörper ist unkonjugiert

Applikation: ELISA (Detection)

Klon: 7G7

Produktdetails anti-EPO Antikörper

Verwendungszweck: Erythropoietin/EPO Monoclonal Antibody(Detector)

Aufreinigung: Protein A/G Purification

Immunogen: Recombinant Mouse Erythropoietin/EPO protein expressed by E.coli

Isotyp: IgM

Anwendungsinformationen

Applikationshinweise: ELISA Detector 0.1-0.4 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Sterile PBS , pH 7.4

Konservierungsmittel: Without preservative

Handhabung: Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C Valid for 1 month or -20°C Valid for 12 months

Haltbarkeit: 12 months

Details zu EPO

Target: EPO (Erythropoietin (EPO))

Andere Bezeichnung: Erythropoietin/EPO

Substanzklasse: Hormone

Hintergrund: MGC,ECYT,MVCD,Hematopoietin,Hemopoietin,ECYT5,EP,epoetin,Erythropoietin,MGC138142,MVCD2,Epo,This gene encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The encoded protein is mainly synthesized in the kidney, secreted into the blood plasma, and binds to the erythropoietin receptor to promote red blood cell production, or erythropoiesis, in the bone marrow. Expression of this gene is upregulated under hypoxic conditions, in turn leading to increased erythropoiesis and enhanced oxygen-carrying capacity of the blood. Expression of this gene has also been observed in brain and in the eye, and elevated expression levels have been observed in diabetic retinopathy and ocular hypertension. Recombinant forms of the encoded protein exhibit neuroprotective activity against a variety of potential brain injuries, as well as antiapoptotic functions in several tissue types, and have been used in the treatment of anemia and to enhance the efficacy of cancer therapies.

UniProt: P07321

Pathways: JAK-STAT Signalweg, Hormone Activity, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity