Endoglin Antikörper

Produktnummer ABIN7670592

Der Kaninchen Polyklonal Anti-Endoglin-Antikörper wurde für ELISA validiert. Er ist geeignet, Endoglin in Proben von Human zu detektieren.

Kurzübersicht für Endoglin Antikörper (ABIN7670592)

Target: Endoglin (ENG)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Endoglin Antikörper ist unkonjugiert

Applikation: ELISA

Produktdetails anti-Endoglin Antikörper

Verwendungszweck: Endoglin/CD105 Polyclonal Antibody(Capture/Detector)

Aufreinigung: Antigen Affinity Purification

Immunogen: Recombinant Human Endoglin/CD105 protein expressed by E.coli

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA Capture 2-8 μg/mL,ELISA Detector 0.1-0.4 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Sterile PBS , pH 7.4

Konservierungsmittel: Without preservative

Handhabung: Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C Valid for 1 month or -20°C Valid for 12 months

Haltbarkeit: 12 months

Details zu Endoglin

Target: Endoglin (ENG)

Andere Bezeichnung: Endoglin/CD105

Hintergrund: ENG,CD105,EndogLin,END,Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis.Required for normal structure and integrity of adult vasculature.Regulates the migration of vascular endothelial cells.Required for normal extraembryonic angiogenesis and for embryonic heart development.May regulate endothelial cell shape changes in response to blood flow,which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis.May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors.Acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade that ultimately leads to the activation of SMAD transcription factors.Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGFB1 signaling through SMAD3.

UniProt: P17813