Cathepsin B Antikörper

Produktnummer ABIN7670553

Der Kaninchen Polyklonal Anti-Cathepsin B-Antikörper wurde für ELISA validiert. Er ist geeignet, Cathepsin B in Proben von Human zu detektieren.

Kurzübersicht für Cathepsin B Antikörper (ABIN7670553)

Target: Cathepsin B (CTSB)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cathepsin B Antikörper ist unkonjugiert

Applikation: ELISA

Produktdetails anti-Cathepsin B Antikörper

Verwendungszweck: Cathepsin B Polyclonal Antibody(Capture/Detector)

Aufreinigung: Antigen Affinity Purification

Immunogen: Recombinant Human Cathepsin B protein expressed by Mammalian

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA Capture 2-8 μg/mL,ELISA Detector 0.1-0.4 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Sterile PBS , pH 7.4

Konservierungsmittel: Without preservative

Handhabung: Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C Valid for 1 month or -20°C Valid for 12 months

Haltbarkeit: 12 months

Details zu Cathepsin B

Target: Cathepsin B (CTSB)

Andere Bezeichnung: Cathepsin B

Hintergrund: APPS,CPSB,CTSB(Cathepsin B) is also named as CPSB and belongs to the peptidase C1 family. It participates in intracellular degradation and turnover of proteins. Cathepsin B precursors found in human malignant ascites fluid do not possess mannose-rich carbohydrates suggesting that a defect in the post translational processing of carbohydrate moieties on tumor. Cathepsin B exists as both glycosylated and unglycosylated forms. In rat macrophages and hepatocytes pro- cathepsin B is 39 kDa (unglycosylated =35 kDa),whereas in human fibroblasts procathepsin B is 44.5-46 kDa (unglycosylated=39 kDa). It can be detected the 43 kDa form of pro-CTSB,31 kDa and 25 kDa mature forms in mouse brain by western blot.

UniProt: P07858

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades