Cadherin 5 Antikörper

Produktnummer ABIN7670546

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Cadherin 5 in ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Cadherin 5 Antikörper (ABIN7670546)

Target: Cadherin 5 (CDH5)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cadherin 5 Antikörper ist unkonjugiert

Applikation: ELISA

Produktdetails anti-Cadherin 5 Antikörper

Verwendungszweck: VE-Cadherin Polyclonal Antibody(Capture/Detector)

Aufreinigung: Antigen Affinity Purification

Immunogen: Recombinant Human VE-Cadherin protein expressed by E.coli

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA Capture 2-8 μg/mL,ELISA Detector 0.1-0.4 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Sterile PBS , pH 7.4

Konservierungsmittel: Without preservative

Handhabung: Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C Valid for 1 month or -20°C Valid for 12 months

Haltbarkeit: 12 months

Details zu Cadherin 5

Target: Cadherin 5 (CDH5)

Andere Bezeichnung: VE-Cadherin

Hintergrund: CDH5,CD144,Cadherin-5,7B4 antigen,VascuLar endotheLiaL cadherin (VE-cadherin),Cadherins are calcium-dependent cell adhesion proteins.They preferentially interact with themselves in a homophilic manner in connecting cells,cadherins may thus contribute to the sorting of heterogeneous cell types.This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions.It associates with alpha-catenin forming a link to the cytoskeleton.Acts in concert with KRIT1 and PAlS1 to establish and maintain correct endothelial cell polarity and vascular lumen.These effects are mediated by recruitment and activation of the Par polarity complex and RAP1B.Required for activation of PRKCZ and for the localization of phosphorylated PRKCZ,PARD3,TIAM1 and RAP1B to the cell junction.

UniProt: P33151

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2