Liver Arginase Antikörper

Produktnummer ABIN7670538

Der Kaninchen Polyklonal Anti-Liver Arginase-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, Liver Arginase in Proben von Ratte und Maus zu detektieren.

Kurzübersicht für Liver Arginase Antikörper (ABIN7670538)

Target: Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Reaktivität: Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Liver Arginase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Liver Arginase Antikörper

Verwendungszweck: Arginase 1/ARG1 Polyclonal Antibody(Capture/Detector)

Aufreinigung: Antigen Affinity Purification

Immunogen: Recombinant Mouse Arginase 1/ARG1 protein expressed by E.coli

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000,ELISA Capture 2-8 μg/mL,ELISA Detector 0.1-0.4 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Sterile PBS , pH 7.4

Konservierungsmittel: Without preservative

Handhabung: Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C Valid for 1 month or -20°C Valid for 12 months

Haltbarkeit: 12 months

Details zu Liver Arginase

Target: Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Andere Bezeichnung: Arginase 1

Hintergrund: Arg1,Arginase-1,Liver-type arginase,Type I arginase,Arginase is the focal enzyme of the urea cycle hydrolysing l-arginine to urea and l-ornithine. Emerging studies have identified arginase in the vasculature and have implicated this enzyme in the regulation of nitric oxide (NO) synthesis and the development of vascular disease. Arginase also redirects the metabolism of l-arginine to l-ornithine and the formation of polyamines and l-proline,which are essential for smooth muscle cell growth and collagen synthesis. Arginase is encoded by two recently discovered genes (Arginase I and Arginase II). In most mammals,Arginase 1 (ARG1) also known as Arginase,liver,which functions in the urea cycle,and is located primarily in the cytoplasm of the liver. The second isozyme,Arginase II,has been implicated in the regulation of the arginine/ornithine concentrations in the cell. It is located in mitochondria of several tissues in the body,with most abundance in the kidney and prostate. It may be found at lower levels in macrophages,lactating mammary glands,and brain.

Molekulargewicht:

Calculated MW: 34kDa

ObservedMW: 40kDa

UniProt: Q61176

Pathways: Cellular Response to Molecule of Bacterial Origin