Cathepsin L Antikörper

Produktnummer ABIN7670502

Der Kaninchen Polyklonal Anti-Cathepsin L-Antikörper wurde für IHC validiert. Er ist geeignet, Cathepsin L in Proben von Human zu detektieren.

Kurzübersicht für Cathepsin L Antikörper (ABIN7670502)

Target: Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cathepsin L Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktdetails anti-Cathepsin L Antikörper

Verwendungszweck: Cathepsin L Polyclonal Antibody

Aufreinigung: Antigen Affinity Purification

Immunogen: Recombinant Human Cathepsin L protein expressed by Mammalian

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:500-1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.05 % proclin 300, 1 % protective protein and 50 % glycerol, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu Cathepsin L

Target: Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))

Andere Bezeichnung: Cathepsin L

Hintergrund: CATL,CATL1,CTSL,CTSL1,Cathepsin L1,Cathepsin L1 light chain,CathepsinL,FLJ31037,MEP,MGC123162,Major excreted protein,cathepsin L,cb15,ctsl1b,hgg1,The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Multiple alternatively spliced transcript variants have been found for this gene.

UniProt: P07711

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades