IL2 Receptor beta Antikörper
Kurzübersicht für IL2 Receptor beta Antikörper (ABIN7670185)
Target
Alle IL2 Receptor beta (IL2RB) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- AF/LE Purified Anti-Human CD122 Antibody[TU27]
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Endotoxin-Niveau
- Low Endotoxin
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Isotyp
- IgG1, kappa
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- ≥ 1 mg/mL
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Buffer
- Sterile PBS. < 1.0 EU per mg of the antibody as determined by the LAL method.
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Konservierungsmittel
- Azide free
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Handhabung
- avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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Haltbarkeit
- 12 months
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- IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
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Andere Bezeichnung
- CD122
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Hintergrund
- P70;IL2RB;CD122;IL15RB;P70-75;IL-2Rβ;p75;IL-2RB;Interleukin-2 receptor subunit beta;IL-2 receptor subunit beta;IL-2R subunit beta;High affinity IL-2 receptor subunit beta;Interleukin-15 receptor subunit beta;p70-75 (p75);IL-2RβCD122 antigen;High affinity IL 2 receptor beta subunit;High affinity IL 2 receptor subunit beta;IL2 receptor;Interleukin 2 receptor beta;interleukin 2 receptor subunit beta;P70 75;P7075,Functional IL-2 receptors can exist in two affinity states on cell surfaces, the high affinity complex consisting of heterotrimers of the alpha, beta, and gamma chains and the intermediate affinity complex comprising heterodimers of the beta and gamma chains. Individual beta chains and alpha chains exhibit low affinity IL-2 binding, and the gamma chain alone does not bind IL-2. In addition to their involvement in IL-2 mediated signal transduction, both the beta chain and gamma chain have been shown to be required for IL-15 mediated signaling. IL-2 R beta is a member of the cytokine receptor superfamily.
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UniProt
- P14784
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Pathways
- JAK-STAT Signalweg, Growth Factor Binding
Target
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