CD86 Antikörper

Produktnummer ABIN8064972

Der Maus Monoklonal anti-CD86 Antikörper (Klon IT2-2) (ABIN8064972) detektiert spezifisch CD86 in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für CD86 Antikörper (ABIN8064972)

Target: CD86

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD86 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: IT2-2

Produktdetails anti-CD86 Antikörper

Verwendungszweck: AF/LE Purified Anti-Human CD86 Antibody[IT2.2]

Endotoxin-Niveau: Low Endotoxin

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: ≥ 1 mg/mL

Buffer: Sterile PBS. < 1.0 EU per mg of the antibody as determined by the LAL method.

Konservierungsmittel: Azide free

Handhabung: avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Haltbarkeit: 12 months

Details zu CD86

Target: CD86

Andere Bezeichnung: CD86

Hintergrund: T-lymphocyte activation antigen CD86,Cd86,Activation B7-2 antigen,Early T-cell costimulatory molecule 1,ETC-1,This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.

UniProt: P42081

Pathways: T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation